Selective, high affinity 5-HT6
= 20 nM). Reverses the amnesic effects of scopolamine
(Cat. No. 1414) and enhances memory consolidation in a rat model.
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BGC20-761, a novel tryptamine analog, enhances memory consolidation and reverses scopolamine-induced memory deficit in social and visuospatial memory tasks through a 5-HT6 receptor-mediated mechanism.
Mitchell et al.
2-Substituted tryptamines: Agents with selectivity for 5-HT6 serotonin receptors.
Glennon et al.