BHPI
Tocris Bioscience | Catalog # 6116
Key Product Details
Description
Product Description
BHPI is an estrogen receptor (ER) α inhibitor. Inhibits proliferation of drug-resistant ERα-positive breast and ovarian cancer cells. Induces sustained activation of the unfolded protein response. Active in vivo.
Product Specifications for BHPI
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.14 | 100 | |
| Ethanol | 33.14 | 100 |
Preparing Stock Solutions for BHPI
The following data is based on the product molecular weight 331.36.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.02 mL | 15.09 mL | 30.18 mL |
| 5 mM | 0.60 mL | 3.02 mL | 6.04 mL |
| 10 mM | 0.30 mL | 1.51 mL | 3.02 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.60 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Andruska Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression. Proc.Natl.Acad.Sci.U.S.A. 2015 PMID: 25825714
Product Documents for BHPI
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for BHPI
For research use only
Related Research Areas
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