BIIE 0246 hydrochloride

Catalog # Availability Size / Price Qty
7377/10
7377/1
BIIE 0246 hydrochloride | CAS No. 246146-31-6 | NPY Receptor Antagonists
1 Image
Description: Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
Alternative Names: BIIE 0246 2HCl,BIIE0246 2HCl

Chemical Name: N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide dihydrochloride

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

BIIE 0246 hydrochloride is a potent, selective and competitive nonpeptide antagonist for the neuropeptide Y Y2 receptor (IC50 = 15 nM). Displays > 650-fold selectivity for NPY Y2 over Y1, Y4 and Y5 receptors. Active in vivo.

Technical Data

M.Wt:
968.98
Formula:
C49H57N11O6.2HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
246146-31-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
View Batch
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for BIIE 0246 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for BIIE 0246 hydrochloride include:

2 Citations: Showing 1 - 2

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for BIIE 0246 hydrochloride

There are currently no reviews for this product. Be the first to review BIIE 0246 hydrochloride and earn rewards!

Have you used BIIE 0246 hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.