BMS 309403

Catalog # Availability Size / Price Qty
5258/10
5258/50
BMS 309403 | CAS No. 300657-03-8 | Additional Lipid Metabolism Compounds
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Description: Potent and selective FABP4 inhibitor

Chemical Name: 2-[[2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]-acetic acid

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

BMS 309403 is a potent and selective fatty acid binding protein 4, adipocyte (FABP4) inhibitor (Ki values are <2, 250 and 350 nM for FABP4, FABP3 and FABP5 respectively). Decreases fatty acid uptake in adipocytes in vitro and reduces atherosclerotic lesion area in a mouse model of atherosclerosis. Reduces blood glucose levels and increases insulin sensitivity in a mouse model of obesity. Orally active.

Technical Data

M.Wt:
474.55
Formula:
C31H26N2O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
300657-03-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for BMS 309403

The citations listed below are publications that use Tocris products. Selected citations for BMS 309403 include:

2 Citations: Showing 1 - 2

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