BMS 566419

Catalog # Availability Size / Price Qty
5492/10
5492/50
Cat.No. 5492 - BMS 566419 | C28H30FN5O2 | CAS No. 566161-24-8
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Description: Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

Chemical Name: N-[1-[6-(4-Ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent inosine monophosphate dehydrogenase (IMPDH) inhibitor (IC50 = 17 nM). Inhibits proliferation of human T-lymphoblasts and PBMCs in vitro. Reduces paw swelling in a rat adjuvant arthritis model. Orally available.

Technical Data

M.Wt:
487.57
Formula:
C28H30FN5O2
Solubility:
Soluble to 50 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
566161-24-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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