BMS CCR2 22

Catalog # Availability Size / Price Qty
3129/10
3129/50
3129/1
Chemokine Receptor Antagonists Small Molecule
1 Image
Description: High affinity, potent CCR2 antagonist

Chemical Name: 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide

Purity: ≥98%

Product Details
Citations (3)
Supplemental Products
Reviews

Biological Activity

High affinity CCR2 chemokine receptor antagonist (IC50 = 5.1 nM). Displays potent functional antagonism, IC50 values are 1 and 18 nM for chemotaxis and antagonism of calcium flux respectively. Selective over CCR3.

Technical Data

M.Wt:
593.66
Formula:
C28H34F3N5O4S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
445479-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for BMS CCR2 22

The citations listed below are publications that use Tocris products. Selected citations for BMS CCR2 22 include:

3 Citations: Showing 1 - 3

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