BQ-3020

Tocris Bioscience | Catalog # 1189

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Citations (4)

Product Documents

Selective ETB agonist

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Selective ETB agonist

View all Endothelin ETB Receptor Agonists »

Product Description

BQ-3020 is a highly potent and selective ET_B endothelin receptor agonist (K_i values are 0.18 and 970 nM at human ET_B and ET_A receptors respectively).

Product Specifications for BQ-3020

Molecular Weight

2006.35

Formula

C₉₆H₁₄₀N₂₀O₂₅S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

143113-45-5

PubChem ID

16135850

InChI Key

AYJUXFCWNAVJLN-FHOIYVHLSA-N

SMILES

CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 0.5mg/ml in sodium bicarbonate (0.03M)

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Sakamoto Distinct subdomains of human endothelin receptors determine their selectivity to endothelin_A-selective antagonist and endothelin_B-selective agonists. J.Biol.Chem. 1993 PMID: 8473300
Ihara [₃H]-BQ-123, a highly specific and reversible radioligand for the endothelin ET_A receptor subtype. Eur.J.Pharmacol. 1995 PMID: 7768260
Reynolds Pharmacological differences between rat and human endothelin B receptors. Biochem.Biophys.Res.Commun. 1995 PMID: 7733918
Ekelund Effects of selective ET_B-receptor stimulation on arterial, venous and capillary functions in cat skeletal muscle. Br.J.Pharmacol. 1994 PMID: 7921617

Product Documents for BQ-3020

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for BQ-3020

For research use only

Citations for BQ-3020

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