Catalog Number: 0427
Chemical Name: (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate
Biological Activity
Selective D2-like dopamine receptor agonist (Ki values are ~ 8, ~ 5, ~ 290, ~ 440 and ~ 450 nM for D2, D3, D4, D1 and D5 receptors respectively).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in ethanol and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Bromocriptine produces decreases in cocaine self-administration in the rat.
    Aubner et al.
    Neuropsychopharmacology, 1990;3:101
  2. Bromocriptine in Parkinson disease.
    Lieberman and Goldstein
    Pharmacol.Rev., 1985;37:217
  3. Dopamine receptor pharmacology.
    Seeman and Van Tol
    Trends Pharmacol.Sci., 1994;15:264
  4. The effects of chronic bromocriptine treatment on behaviour and dopamine receptor binding in the rat striatum.
    Traub et al.
    Eur.J.Pharmacol., 1985;118:147

The citations listed below are publications that use Tocris products. Selected citations for Bromocriptine mesylate include:

Showing Results 1 - 1 of 1

  1. Age-dependent regulation of synaptic connections by dopamine D2 receptors.
    Authors: Jia Et al.
    Nat Neurosci
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