Bromosporine

Tocris Bioscience | Catalog # 4758

Broad spectrum bromodomain inhibitor
Tocris Bioscience

Key Product Details

Description

Broad spectrum bromodomain inhibitor
View all Bromodomain Inhibitors »

Product Description

Bromosporine is a broad spectrum bromodomain inhibitor. Accelerates FRAP recovery of BRD4 and CREBBP in cells at a concentration of 1 μM.

Licensing Information

This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the Bromosporine probe summary on the SGC website.

Product Specifications for Bromosporine

Molecular Weight

404.44

Formula

C17H20N6O4S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[(6-3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate

CAS Number

1619994-69-2

PubChem ID

72943187

InChI Key

UYBRROMMFMPJAN-UHFFFAOYSA-N

SMILES

CC1=C(NS(=O)(C)=O)C=C(C3=NN2C(C(NC(OCC)=O)=C3)=NN=C2C)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.44 100

Preparing Stock Solutions for Bromosporine

The following data is based on the product molecular weight 404.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.47 mL 12.36 mL 24.73 mL
5 mM 0.49 mL 2.47 mL 4.95 mL
10 mM 0.25 mL 1.24 mL 2.47 mL
50 mM 0.05 mL 0.25 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Bromosporine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Bromosporine

For research use only

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