Chemical Name: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone
Biological ActivityBropirimine is a immunomodulatory and antitumor compound. Induces interferon (IFN)-α/β production; augments natural killer (NK) cell activity. Orally active.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Antitumor effects of oral administration of an IF.-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma.
Fujioka et al.
Cancer Chemother.Pharmacol., 1995;36:7
In vitro antitumor activity of bropirimine against urinary bladder tumor cells.
Tei et al.
Anticancer Res., 2002;22:1667
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Immuno-therapeutic effect of Bropirimine was studied against other immunomodulatory imide drugs.