C 021 dihydrochloride

Catalog # Availability Size / Price Qty
3581/10
3581/50
C 021 dihydrochloride | CAS No. 1784252-84-1 | Chemokine Receptor Antagonists
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Description: Potent CCR4 antagonist

Chemical Name: 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride

Purity: ≥99%

Product Details
Citations (5)
Supplemental Products
Reviews (1)

Biological Activity

Potent CCR4 chemokine receptor antagonist (IC50 values are 0.14 and 0.039 μM for inhibition of chemotaxis in human and mouse respectively).

Technical Data

M.Wt:
540.57
Formula:
C27H41N5O2.2HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
1784252-84-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for C 021 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for C 021 dihydrochloride include:

5 Citations: Showing 1 - 5

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Reviews for C 021 dihydrochloride

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Unfortunately I found no effect.
By Anonymous on 12/12/2017
Species: Human

I used it both in vivo and in vitro. In vitro, I was unable to find any impact in chemotaxis towards CCL17


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