C-Laurdan

Key Product Details

Product Description

Key information: C-Laurdan is a polarity-sensitive lipid membrane probe.

Used for: lipid raft imaging and cell membrane imaging.

Application: One and two-photon microscopy for membrane polarity.

Properties and Photophysical Data: C-laurdan carry a carboxylic group which can be partially ionized which contributes to its good water solubility and fast membrane incorporation. Two photon excitation spectra = 780 nm. One photon excitation and emission maxima (λ) are 348 nm and 423 nm, respectively; quantum yield = 0.43; extinction coefficient = 12,200 M^-1cm^-1.

Optical Data

Product Specifications for C-Laurdan

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for C-Laurdan

The following data is based on the product molecular weight 397.56.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.52 mL	12.58 mL	25.15 mL
5 mM	0.50 mL	2.52 mL	5.03 mL
10 mM	0.25 mL	1.26 mL	2.52 mL
50 mM	0.05 mL	0.25 mL	0.50 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

• Barucha-Kraszewska Will C-Laurdan dethrone Laurdan in fluorescent solvent relaxation techniques for lipid membrane studies? Langmuir 2013 PMID: 23311388
• Mazeres Characterization of M-laurdan, a versatile probe to explore order in lipid membranes. F1000Res. 2014 PMID: 25485094
• Kim A two-photon fluorescent probe for lipid raft imaging: C-laurdan. Chembiochem 2007 PMID: 17300111

Product Documents for C-Laurdan