CCK agonist. Stimulates biosynthesis of pancreatic enzymes in AR4-2J pancreatic cells in vitro
. Induces acute pancreatitis in mice. Also enhances proteasome activity in Gdeg
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Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma.
Murakami et al.
Proteasome activity is required for the initiation of precancerous pancreatic lesions.
Furuyama et al.
Caerulein and gastrin(2-17 ds) regulate differently synthesis of secretory enzymes, mRNA levels and cell proliferation in pancreatic acinar cells (AR4-2J).
Pradel et al.