Catalog Number: 2743
Alternate Names: CAPE
Chemical Name: 3-(3,4-Dihydroxyphenyl)-2-propenoic acid 2-phenylethyl ester
Biological Activity
Antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral. Specifically inhibits NF-κB activation and inhibits the growth of transformed cells. Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties.
    Sud'ina et al.
    FEBS Lett., 1993;329:21
  2. Caffeic acid phenethyl ester, an inhibitor of nuclear factor-κB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats.
    Fitzpatrick et al.
    J.Pharmacol.Exp.Ther., 2001;299:915
  3. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB.
    Natarajan et al.
    Proc.Natl.Acad.Sci.USA, 1996;93:9090
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