Catalog Number: 1935
Chemical Name: N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-glutamic acid
Biological Activity
Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE, Cat. No. 1927).
Technical Data
  • M.Wt:
    923.82
  • Formula:
    C39H50N5O19P
  • Sequence:
    YEEIE

    (Modifications: Tyr-1 = N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-)-pTyr, Glu-2 = αGlu, Glu-3 = αGlu)

  • Storage:
    Desiccate at -20°C
  • CAS No:
    507471-72-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Design and characterization of non-phosphopeptide inhibitors for src family SH2 domains.
    Park et al.
    Bioorg.Med.Chem.Lett., 2002;12:2711
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Caffeic acid-pYEEIE include:

1 Citations: Showing 1 - 1

  1. A selective NMR probe to monitor the conformational transition from inactive to active kinase.
    Authors: Xie Et al.
    J Neurosci 2015;10:262

Have you used Caffeic acid-pYEEIE?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Feedback

Customer Information