Central nervous system stimulant. Antagonist at A1
adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases. Mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors.
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All Tocris products are intended for laboratory research use only.
Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects.
Nehlig et al.
Brain Res.Brain Res.Rev., 1992;17:139
Caffeine as a psychomotor stimulant: mechanism of action.
Fisone et al.
Cell.Mol.Life Sci., 2004;61:857
Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease.
Chen et al.
The citations listed below are publications that use Tocris products. Selected citations for Caffeine include:
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