Catalog Number: 4036
Alternate Names: 25-Hydroxyvitamin D3, Calcidiol
Chemical Name: (εR,1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-α,α,ε,7a-tetramethyl-1H-indene-1-pentanol
Biological Activity
Prohormone of calcitriol (Cat. No. 2551). Major circulating form of vitamin D. Suppresses PTH synthesis and secretion in bovine parathyroid cells (ED50 = 2 nM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble in DMSO and in ethanol
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells.
    Rowling et al.
    J.Nutr., 2006;136:2754
  2. Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control study.
    Fedirko et al.
    Am.J.Epidemiol., 2010;172:489
  3. 25-hydroxyvitamin D3 suppresses PTH synthesis and secretion by bovine parathyroid cells.
    Ritter et al.
    Kidney Int., 2006;70:654

The citations listed below are publications that use Tocris products. Selected citations for Calcifediol include:

Showing Results 1 - 1 of 1

  1. Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells.
    Authors: Kim Et al.
    Biochim Biophys Acta
Tocris Small Molecules
Description Application Cat# Citations Images  


2551 2  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Vitamin D3

4156 2  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information