CaM Kinase I Antibody (010) [Biotin]

Novus Biologicals | Catalog # NBP2-90023B

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Biotin

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 010 expressed in HEK293
View all CaM Kinase I Primary Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human CaM Kinase I (Accession#: NP_003647.1; Leu2-Leu370).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for CaM Kinase I Antibody (010) [Biotin]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CaM Kinase I

Ca(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3)

Long Name

Calcium/Calmodulin-dependent Protein Kinase I

Alternate Names

calcium/calmodulin-dependent protein kinase I, calcium/calmodulin-dependent protein kinase type 1, CaM kinase I, CaM kinase I alpha, CaMKI, CaM-KI, caMKI-alpha, EC 2.7.11, EC 2.7.11.17, MGC120317, MGC120318

Gene Symbol

CAMK1

Additional CaM Kinase I Products

Product Documents for CaM Kinase I Antibody (010) [Biotin]

Certificate of Analysis

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Product Specific Notices for CaM Kinase I Antibody (010) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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