Camptothecin

  ( 5 citations )    
Product Datasheet
Catalog Number:1100
Chemical Name:(S)-4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Cytotoxic plant alkaloid with antitumor properties; prototypic DNA topoisomerase I inhibitor. Induces single strand DNA breaks and protein-DNA crosslinks.
Technical Data
  • M.Wt:
    348.36
  • Formula:
    C20H16N2O4
  • Solubility:
    Soluble to 5 mM in DMSO
  • Purity:
    >98
  • Storage:
    Desiccate at +4°C
  • CAS No:
    7689-03-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Camptothecin include:

5 Citations: Showing 1 - 5
Filter your results:

  1. CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia.
    Authors: Neveu Et al.
    Haematologica  2016;
  2. Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status.
    Authors: Lamy Et al.
    PLoS One  2013;8:e70846
  3. Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.
    Authors: Gründemann Et al.
    PLoS One  2013;8:e68016
  4. Immunosuppressive activity of an aqueous Viola tricolor herbal extract.
    Authors: Hellinger Et al.
    J Ethnopharmacol  2013;151:299
  5. Oxygen-sensitive {δ}-opioid receptor-regulated survival and death signals: novel insights into neuronal preconditioning and protection.
    Authors: Ma Et al.
    Sci Rep  2005;280:16208

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used Camptothecin?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee