(-)-Cannabidiol

  ( 2 citations )    
Product Datasheet
Catalog Number:1570
Alternate Names:CBD
Chemical Name:2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Non-psychotropic constituent of cannabis that is anticonvulsive, antihyperalgesic and neuroprotective in vivo. GPR55 and weak CB1 antagonist (IC50 values are 0.445 and 3.35 μM), CB2 receptor inverse agonist and inhibitor of anandamide uptake (IC50 = 27.5 μM). Also a weak agonist at VR1 vanilloid receptors (EC50 = 3.5 μM).
Technical Data
  • M.Wt:
    314.47
  • Formula:
    C21H30O2
  • Solubility:
    Soluble to 75 mM in ethanol and to 75 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    13956-29-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (-)-Cannabidiol include:

2 Citations: Showing 1 - 2
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  1. Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement.
    Authors: Esposito Et al.
    Proc Natl Acad Sci U S A  2011;6:e28668
  2. The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.
    Authors: Whyte Et al.
    PLoS One  2009;106:16511

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