Caspase-8 Antibody Blocking Peptide
Novus Biologicals | Catalog # NBP1-76610PEP
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Key Product Details
Source
Synthetic
Applications
Antibody Competition
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Product Specifications
Description
A blocking peptide containing 16 amino acids near the carboxy terminus of human Caspase-8 isoform A.
Source: Synthetic
(Accession #: NP_001219)
Application Notes
This peptide is useful as a blocking peptide for NBP1-76610.
For further blocking peptide related protocol, click here.
For further blocking peptide related protocol, click here.
Protein / Peptide Type
Antibody Blocking Peptide
Formulation, Preparation, and Storage
NBP1-76610PEP
| Formulation | PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin. |
| Preservative | 0.02% Sodium Azide |
| Concentration | 0.2 mg/ml |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -20C. Avoid freeze-thaw cycles. |
Background: Caspase-8
Caspase 8 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 8 form.
Caspase 8 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.
Alternate Names
CASP8, Caspase8, Mch5
Gene Symbol
CASP8
Additional Caspase-8 Products
Product Documents for Caspase-8 Antibody Blocking Peptide
Product Specific Notices for Caspase-8 Antibody Blocking Peptide
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
Related Research Areas
Citations for Caspase-8 Antibody Blocking Peptide
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FAQs for Caspase-8 Antibody Blocking Peptide
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Q: May we ask the MW difference between the active form and the proform of Caspase 8 while performing WB?
A: In treated cells induced to undergo apoptosis, caspase-8 migrates as a 55/53 kDa (pro-form), 41/42 kDa (a cleaved/active or intermediate form), and 18 kDa (active form). The proform (55/53 kDa) is still seen in treated cells because not all cells undergo apoptosis at once.
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