Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG2A Clone # 212211
View all Cathepsin E Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Cathepsin E
Gln18-Pro396
Accession # NP_001901

Specificity

Detects human Cathepsin E in direct ELISAs and Western blots. It recognizes both the pro and mature forms of recombinant human (rh) Cathepsin E. In Western blots, 100% cross‑reactivity with recombinant mouse (rm) Cathepsin E and recombinant human (rh) BACE is observed under reducing conditions. Under non-reducing conditions, less than 1% cross-reactivity with rmCathepsin E and rhBACE-1 is observed. Less than 1% cross-reactivity with rhCathepsin D is observed under both reducing and non-reducing conditions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Applications for Cathepsin E Antibody (212211) [Janelia Fluor® 646]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product MAB1294. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cathepsin E

Cathepsin E (CATE) is a gastric aspartyl protease member of the peptidase C1 family that functions as a disulfide-linked homodimer. Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. Cathepsin E may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

Cathepsin E is commonly linked to gastric cancer, and Cathepsin E antibodies have emerged as important reagents for gastric cancer studies.

Alternate Names

CTSE

Gene Symbol

CTSE

Additional Cathepsin E Products

Product Documents for Cathepsin E Antibody (212211) [Janelia Fluor® 646]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Cathepsin E Antibody (212211) [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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