Human Cathepsin F ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) CV% 6.3 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 10.3 (example only; lot dependent)

Recovery for Human Cathepsin F ELISA Kit (Colorimetric)

Scientific Data Images for Human Cathepsin F ELISA Kit (Colorimetric)

Preparation and Storage

Background: Cathepsin F

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

Additional Cathepsin F Products

• All Products for Cathepsin F
• Cathepsin F ELISA Kits
• Cathepsin F Primary Antibodies
• Cathepsin F Proteins and Enzymes

Product Documents for Human Cathepsin F ELISA Kit (Colorimetric)