CCG 1423

Catalog # Availability Size / Price Qty
5233/10
5233/50

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CCG 1423 | CAS No. 285986-88-1 | Rho GTPase Inhibitors
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Description: Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs

Chemical Name: N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)benzamide

Purity: ≥99%

Product Details
Reviews

Biological Activity

CCG 1423 is a Rho/SRF pathway inhibitor; stimulates apoptosis of a melanoma cell line overexpressing RhoC (A375M2). Suppresses Rho-dependent invasion of PC-3 prostate cancer cells in vitro and inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer cells. When used in combination with Retinoic acid, LY 294002 and Pyridone 6, it induces intermediate mesoderm differentiation from ESCs.

Technical Data

M.Wt:
454.75
Formula:
C18H13ClF6N2O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
285986-88-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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