Retinoic acid

Catalog # Availability Size / Price Qty
0695/50
Retinoic acid | CAS No. 302-79-4 | Retinoic Acid Receptor Agonists
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Description: Endogenous retinoic acid receptor agonist
Alternative Names: Tretinoin, ATRA

Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid

Purity: ≥99%

Product Details
Citations (6)
Reviews

Biological Activity

Endogenous agonist for retinoic acid receptors (IC50 = 14 nM for RARα, RARβ and RARγ receptors). Also promotes differentiation of mouse embryonic stem cells (ESCs) into adipocytes, neurons and glia in vitro. Proposed ligand of RORβ (Kd = 280 nM). Activates autophagy.

Technical Data

M.Wt:
300.44
Formula:
C20H28O2
Solubility:
Soluble to 25 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
302-79-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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⚠ WARNING: This product can expose you to chemicals including All-trans retinoic acid, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for Retinoic acid

The citations listed below are publications that use Tocris products. Selected citations for Retinoic acid include:

6 Citations: Showing 1 - 6

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