CCR5 Antibody (T21/8) [PE]

Novus Biologicals | Catalog # NBP2-00325

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # T21/8
View all CCR5 Primary Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody was CCR5.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CCR5 Antibody (T21/8) [PE]

Flow Cytometry: CCR5 Antibody (T21/8) [PE] [NBP2-00325] - Staining of normal human peripheral blood cells with Anti-Human CD3 APC and Mouse IgG1 kappa Isotype Control PE (left) or Anti-Human CD195 (CCR5) PE (right). Cells in the lymphocyte gate were used for analysis.

Applications for CCR5 Antibody (T21/8) [PE]

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Spectra Viewer

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.2) with 0.1% gelatin and 0.2% BSA

Preservative

0.09% Sodium Azide

Concentration

5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CCR5

The T21/8 monoclonal antibody reacts with the amino terminus of human CCR5 (CD195), an approximately 45 kDa member of the G protein-coupled receptor (GPCR) superfamily that binds chemokines including MIP-1a, MIP-1B and RANTES. Human CCR5 is expressed on resting T cells with a memory/effector phenotype, monocytes, macrophages and immature dendritic cells. CCR5 functions as a receptor to direct the chemotaxis of lymphocytes, and is the primary co-receptor for macrophage-tropic Human Immunodeficiency Virus Type 1 (HIV-1), which binds CCR5 through gp120. Binding of the T21/8 monoclonal antibody displays donor variability and may be affected by sub-optimal staining conditions.

Alternate Names

CCR5, CD195

Gene Symbol

CCR5

Additional CCR5 Products

Product Documents for CCR5 Antibody (T21/8) [PE]

Certificate of Analysis

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Product Specific Notices for CCR5 Antibody (T21/8) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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