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CCT 031374 hydrobromide

4675 1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4675/10
4675/50
Cat.No. 4675 - CCT 031374 hydrobromide | C23H19N3O.HBr | CAS No. 1219184-91-4
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Description: Inhibits TCF-dependent transcription; lowers β-catenin levels

Chemical Name: 1-[1,1'-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Inhibitor of TCF-dependent transcription. Blocks BIO-induced β-catenin stabilization; reduces nuclear and cytosolic β-catenin levels in mouse L-cells. Inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells.

Technical Data

M.Wt:
434.33
Formula:
C23H19N3O.HBr
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1219184-91-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for CCT 031374 hydrobromide

The citations listed below are publications that use Tocris products. Selected citations for CCT 031374 hydrobromide include:

1 Citation: Showing 1 - 1

  1. β-catenin signaling induces the osteoblastogenic differentiation of human pre-osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression.
    Authors: Liu Et al.
    Nature  2015;36:1572

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VersaClone cDNA Plasmids

Human beta-Catenin (NP_001895) VersaClone cDNA

RDC2388

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