CD44, variant 4 Antibody - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-49576

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG Kappa

Format

Azide and BSA Free
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Product Specifications

Immunogen

Recombinant fragment corresponding to the v4 domain of human CD44 (Uniprot: P16070)

Localization

Cell membrane, Cell projection, Microvillus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG Kappa

Description

Purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS WITHOUT BSA at 1.0mg/ml. Also available with 0.05% BSA & 0.05% azide at 200ug/ml.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous.

Scientific Data Images for CD44, variant 4 Antibody - Azide and BSA Free

CD44, variant 4 Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: CD44, variant 4 Antibody - Azide and BSA Free [NBP3-49576] -

Formalin-fixed, paraffin-embedded human Cervical Squamous Cell Carcinoma stained with CD44, variant 4 Antibody - Azide and BSA Free.

Applications for CD44, variant 4 Antibody - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: CD44, variant 4

CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.

Alternate Names

CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2CD44 antigen (homing function and Indian blood group system), MDU3CDW44, MIC4MGC10468, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I

Gene Symbol

CD44

Additional CD44, variant 4 Products

Product Documents for CD44, variant 4 Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD44, variant 4 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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