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CELT-133 | Fluorescent Receptor Probes
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Description: Selective hα1A adrenergic receptor fluorescent antagonist

Purity: ≥95%

Product Details

Biological Activity

CELT-133 is a selective hα1A adrenergic receptor fluorescent antagonist. It shows full selectivity for α1A over α2A (Ki= 5 nM and 15% of displacement at 1 μM respectively in radioligand binding assay). CELT-133 binds equally to all subtypes of α1 adrenergic receptor. Excitation and emission maxima (λ) are 560 and 571 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.

Add 76 μL of assay buffer containing 1% of DMSO to obtain a 100 μM stock solution, and use 250 nM as a working concentration.

Optical Data for CELT-133

Emission Color Yellow
λabs 560 nm
λem 571 nm
Application Fluorescence polarization, Confocal microscopy, High content screening

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Technical Data

Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from Celtarys Research

Product Datasheets

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Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).


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