CELT-133

Tocris Bioscience | Catalog # 7952

Selective hα1A adrenergic receptor fluorescent antagonist
Tocris Bioscience

Key Product Details

Description

Selective hα1A adrenergic receptor fluorescent antagonist

Wavelength

Excitation = 560 nm, Emission = 571 nm
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Product Description

CELT-133 is a selective hα1A adrenergic receptor fluorescent antagonist. It shows full selectivity for α1A over α2A (Ki= 5 nM and 15% of displacement at 1 μM respectively in radioligand binding assay). CELT-133 binds equally to all subtypes of α1 adrenergic receptor. Excitation and emission maxima (λ) are 560 and 571 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.

Add 76 μL of assay buffer containing 1% of DMSO to obtain a 100 μM stock solution, and use 250 nM as a working concentration.

Licensing Information

Sold under license from Celtarys Research

Optical Data

Emission Color Yellow
λabs 560 nm
λem 571 nm
Application Fluorescence polarization, Confocal microscopy, High content screening

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Product Specifications for CELT-133

Molecular Weight

1318.43

Storage

Store at -20°C

Purity

≥95% (HPLC)

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for CELT-133

Certificate of Analysis

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Product Specific Notices for CELT-133

For research use only

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