CEP 1347

Catalog # Availability Size / Price Qty
4924/1
CEP 1347 | CAS No. 156177-65-0 | JNK/c-jun Inhibitors
1 Image
Description: Inhibitor of JNK signaling

Chemical Name: (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester

Purity: ≥97%

Product Details
Citations (1)
Reviews

Biological Activity

Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20 nM). Blocks Aβ-induced cortical neuron apoptosis (EC50 ~51 nM). Does not inhibit ERK1 activity. Neuroprotective.

Technical Data

M.Wt:
615.76
Formula:
C33H33N3O5S2
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
156177-65-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for CEP 1347

The citations listed below are publications that use Tocris products. Selected citations for CEP 1347 include:

1 Citation: Showing 1 - 1

  1. WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis.
    Authors: Prinz Et al.
    Mol Biol Cell  2018;29:2470

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for CEP 1347

There are currently no reviews for this product. Be the first to review CEP 1347 and earn rewards!

Have you used CEP 1347?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.