CEP

Tocris Bioscience | Catalog # 8108

Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells
Tocris Bioscience
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Key Product Details

Description

Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells

Product Description

CEP is a chemoproteomic reagent. It is a clickable electrophilic purine used to directly quantify protein-RNA interactions on proteins through photoaffinity competition with 4-thiouridine (4SU)-labeled RNA in cells. It is a cysteine reactive probe used in photo-activatable-competition and chemoproteomic enrichment (PACCE) method for global quantification of protein-RNA interactions in living cells.

Product Specifications for CEP

Molecular Weight

227.05

Formula

C8H4Cl2N4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2,6-Dichloro-7-(2-propyn-1-yl)-7H-purine

CAS Number

1838570-66-3

PubChem ID

155590179

InChI Key

DQZMJDUCMIRFBJ-UHFFFAOYSA-N

SMILES

ClC1=NC(N=CN2CC#C)=C2C(Cl)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 22.7 100
Ethanol 2.27 10 with gentle warming

Preparing Stock Solutions for CEP

The following data is based on the product molecular weight 227.05.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.40 mL 22.02 mL 44.04 mL
5 mM 0.88 mL 4.40 mL 8.81 mL
10 mM 0.44 mL 2.20 mL 4.40 mL
50 mM 0.09 mL 0.44 mL 0.88 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for CEP

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CEP

For research use only

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