Cetrorelix Acetate

Catalog # Availability Size / Price Qty
3536/1
Cetrorelix Acetate
1 Image
Description: Potent GnRH receptor antagonist
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Biological Activity

Potent gonadotropin-releasing hormone (GnRH) receptor antagonist (KD = 0.202 nM, IC50 = 1.21 nM). Suppresses production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, which inhibits ovulation. Exhibits antiproliferative effects and displays efficacy against hormone-sensitive cancers in vivo. Also exhibits anxiolytic and antidepressant activity in vivo.

Technical Data

M.Wt:
1491.11
Formula:
C70H92ClN17O14.C2H4O2
Sequence:
XFASYXLRPA

(Modifications: X-1 = D-2-Nal and N-terminal Ac, Phe-2 = D-(4-Cl-Phe), Ala-3 = D-(3-Pyridyl-Ala), X-6 = D-Cit, Ala-10 = D-Ala and C-terminal amide)

Solubility:
Soluble in water
Storage:
Store at -20°C
CAS No:
145672-81-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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