Cetrorelix Acetate

   
Product Datasheet
Catalog Number:3536
Chemical Name:
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Biological Activity
Potent gonadotropin-releasing hormone (GnRH) receptor antagonist (KD = 0.202 nM, IC50 = 1.21 nM). Suppresses production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, which inhibits ovulation. Exhibits antiproliferative effects and displays efficacy against hormone-sensitive cancers in vivo. Also exhibits anxiolytic and antidepressant activity in vivo.
Technical Data
  • M.Wt:
    1491.11
  • Formula:
    C70H92ClN17O14.C2H4O2
  • Sequence:
    XFASYXLRPA

    (Modifications: X-1 = D-2-Nal and N-terminal Ac, Phe-2 = D-(4-Cl-Phe), Ala-3 = D-(3-Pyridyl-Ala), X-6 = D-Cit, Ala-10 = D-Ala and C-terminal amide)

  • Solubility:
    Soluble in water
  • Storage:
    Store at -20°C
  • CAS No:
    145672-81-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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