CFM 4

Key Product Details

Product Description

CFM 4 is a CARP-1 mimetic; interferes with CARP-1 binding to APC-2. Enhances CARP-1 expression and induces G₂/M cell cycle arrest. Induces apoptosis and suppresses cell growth in cancer cells.

Product Specifications for CFM 4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CFM 4

The following data is based on the product molecular weight 405.90.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	12.32 mL	61.59 mL	123.18 mL
1 mM	2.46 mL	12.32 mL	24.64 mL
2 mM	1.23 mL	6.16 mL	12.32 mL
10 mM	0.25 mL	1.23 mL	2.46 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Ashour CARP-1 functional mimetics: a novel class of small molecule inhibitors of medulloblastoma cell growth. PLoS ONE 2013 PMID: 23826121
• Puliyappadamba Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis. J.Biol.Chem. 2011 PMID: 21903591

Product Documents for CFM 4