CGP 20712 dihydrochloride

Key Product Details

Product Description

CGP 20712 dihydrochloride is a highly selective and potent β₁-adrenoceptor antagonist (IC₅₀ = 0.7 nM). Displays 10,000-fold selectivity over β₂-adrenoceptors.

Product Specifications for CGP 20712 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CGP 20712 dihydrochloride

The following data is based on the product molecular weight 567.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.52 mL	17.62 mL	35.25 mL
2.5 mM	0.70 mL	3.52 mL	7.05 mL
5 mM	0.35 mL	1.76 mL	3.52 mL
25 mM	0.07 mL	0.35 mL	0.70 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 33 publications citing the usage of this product.

• Hieble α-and β-adrenoceptors. From the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification. J.Med.Chem. 1995 PMID: 7658428
• Kitagawa Determination of β-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective β-antagonists. Br.J.Pharmacol. 1995 PMID: 8564230
• Dooley CGP 20712A: a useful tool for quantitating β₁- and β₂-adrenoceptors. Eur.J.Pharmacol. 1986 PMID: 2877892

Product Documents for CGP 20712 dihydrochloride