Human ADRB1 (P08588) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human ADRB1 (P08588) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: beta-1 Adrenergic R/ADRB1

The beta-1 Adrenergic Receptor (ADRB1) belongs to the G protein-coupled receptor 1 family. The adrenergic receptors, including ADRB1, are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine and norepinephrine with approximately equal affinity. ADRB1 is localized at the plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) overexpression. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

Long Name
Beta-1 Adrenergic Receptor
Entrez Gene IDs
153 (Human); 11554 (Mouse); 24925 (Rat)
Alternate Names
ADRB1; ADRB1R; ADRB1RRHR; adrenergic, beta-1-, receptor; B1AR; beta-1 Adrenergic R; beta-1 adrenergic receptor; beta1 AdrenergicR; beta-1 AdrenergicR; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR


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