Catalog Number: 1169
Alternate Names: Calcitonin Gene-Related Peptide 8-37 (rat)
Biological Activity
Peptide antagonist for CGRP1 receptors.
Technical Data
  • M.Wt:
    3127.5
  • Formula:
    C138H224N42O41
  • Sequence:
    VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF

    (Modifications: Phe-30 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    129121-73-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pharmacology of receptors for calcitonin gene-related peptide and amylin.
    Poyner
    TiPS, 1995;16:424
  2. Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides.
    Poyner et al.
    Br.J.Pharmacol., 1998;124:1659
  3. Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens.
    Wisskirchen et al.
    Br.J.Pharmacol., 1998;123:1673
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CGRP 8-37 (rat) include:

1 Citations: Showing 1 - 1

  1. Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception.
    Authors: Holland Et al.
    J Cell Mol Med 2005;315:1380

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