Biological ActivityCGRP (rat) is an endogenous neuropeptide; potent vasodilator which also exerts cardiovascular, pro-inflammatory and metabolic effects.
(Modifications: Disulfide bridge: 2-7, Phe-37 = C-terminal amide)
The technical data provided above is for guidance only.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Calcitonin gene-related peptide is a potent vasodilator.
Brain et al.
Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs.
Nakamura et al.
Brain Res., 1998;807:203
Pharmacology of receptors for calcitonin gene-related peptide and amylin.
Isolation and characterization of human calcitonin gene-related peptide.
Morris et al.
Calcitonin gene-related peptide potentiates nicotinic acetylcholine receptor-operated slow Ca2+ mobilization at mouse muscle endplates.
Salim et al.
Citations for CGRP (rat)
The citations listed below are publications that use Tocris products. Selected citations for CGRP (rat) include:
5 Citations: Showing 1 - 5
Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+).
Authors: Gutierrez and Boada
Cancer Cell Int 2019;18:216
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.
Authors: Iring Et al.
J Clin Invest 2019;130:2775
Distinct calcitonin gene-related peptide expression pattern in primary afferents contribute to different neuropathic symptoms following chronic constriction or crush injuries to the rat sciatic nerve.
Authors: Zou Et al.
Mol Pain 2016;12:1
Release of glutamate and CGRP from trigeminal ganglion neurons: Role of calcium channels and 5-HT1 receptor signaling.
Authors: Xiao Et al.
Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception.
Authors: Holland Et al.
Mol Pain 2005;315:1380
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VersaClone cDNA Plasmids
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