CGS 12066B dimaleate

  ( 2 citations )    
Product Datasheet
Catalog Number:0638
Chemical Name:7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate
Product Details
Citations (2)
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Biological Activity
5-HT1B full agonist, 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Centrally active following systemic administration.
Technical Data
  • M.Wt:
    566.49
  • Formula:
    C17H17F3N4.2C4H4O4
  • Solubility:
    Soluble to 5 mM in water and to 40 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    109028-10-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for CGS 12066B dimaleate include:

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  1. Lasting neurobehavioral abnormalities in rats after neonatal activation of serotonin 1A and 1B receptors: possible mechanisms for serotonin dysfunction in autistic spectrum disorders.
    Authors: Khatri Et al.
    Psychopharmacology (Berl)  2014;231:1191
  2. Evidence that the deficit in sexual behavior in adult rats neonatally exposed to citalopram is a consequence of 5-HT1 receptor stimulation during development.
    Authors: Maciag Et al.
    Brain Res  2006;1125:171

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