full agonist, 10-fold selective over 5-HT1A
and 1000-fold selective over 5-HT2C
receptors. Centrally active following systemic administration.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist?
Schoeffter and Hoyer
Naunyn Schmiedebergs Arch.Pharmacol., 1989;339:675
Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist.
Neale et al.
Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats.
Tomkins and O'Neill
The citations listed below are publications that use Tocris products. Selected citations for CGS 12066B dimaleate include:
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