Chicago Sky Blue 6B

Tocris Bioscience | Catalog # 0846

Dye used as counterstain in histochemistry; also potent inhibitor of L-glutamate uptake into synaptic vesicles; also inhibits MIF
Tocris Bioscience
Discontinued Product
0846 has been discontinued. View all Glutamate (EAAT) Transporter Inhibitors products.

Key Product Details

Description

Dye used as counterstain in histochemistry; also potent inhibitor of L-glutamate uptake into synaptic vesicles; also inhibits MIF
View all Glutamate (EAAT) Transporter Inhibitors »

Product Description

Chicago Sky Blue 6B is a potent inhibitor of L-glutamate uptake into synaptic vesicles. Allosterically inhibits macrophage migration inhibitory factor (MIF) (IC50 = 0.81 μM); inhibits MIF proinflammatory activity. Also dye used as counterstain in histochemistry.

Product Specifications for Chicago Sky Blue 6B

Molecular Weight

992.79

Formula

C34H24N6Na4O16S4

Storage

Store at RT

Chemical Name

6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonic acid] tetrasodium salt

CAS Number

2610-05-1

PubChem ID

102063628

InChI Key

BPHHNXJPFPEJOF-UHFFFAOYSA-J

SMILES

[Na+].[Na+].[Na+].[Na+].COC1=CC(=CC=C1\N=N\C1=C(O)C2=C(C=C1)C(=CC(=C2N)S([O-])(=O)=O)S([O-])(=O)=O)C1=CC(OC)=C(C=C1)\N=N\C1=C(O)C2=C(N)C(=CC(=C2C=C1)S([O-])(=O)=O)S([O-])(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 99.28 100

Preparing Stock Solutions for Chicago Sky Blue 6B

The following data is based on the product molecular weight 992.79.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.01 mL 5.04 mL 10.07 mL
5 mM 0.20 mL 1.01 mL 2.01 mL
10 mM 0.10 mL 0.50 mL 1.01 mL
50 mM 0.02 mL 0.10 mL 0.20 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 13 publications citing the usage of this product.

Product Documents for Chicago Sky Blue 6B

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Chicago Sky Blue 6B

For research use only

Citations for Chicago Sky Blue 6B

Customer Reviews for Chicago Sky Blue 6B

There are currently no reviews for this product. Be the first to review Chicago Sky Blue 6B and earn rewards!

Have you used Chicago Sky Blue 6B?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Staining Kits and Reagents