Chicago Sky Blue 6B

Catalog # Availability Size / Price Qty
Chicago Sky Blue 6B | CAS No. 2610-05-1 | Glutamate (EAAT) Transporter Inhibitors
1 Image
Description: Dye used as counterstain in histochemistry; also potent inhibitor of L-glutamate uptake into synaptic vesicles; also inhibits MIF

Chemical Name: 6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonic acid] tetrasodium salt

Product Details
Citations (1)

Biological Activity

Chicago Sky Blue 6B is a potent inhibitor of L-glutamate uptake into synaptic vesicles. Allosterically inhibits macrophage migration inhibitory factor (MIF) (IC50 = 0.81 μM); inhibits MIF proinflammatory activity. Also dye used as counterstain in histochemistry.

Technical Data

Soluble to 100 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF).
    Bai et al.
    J.Biol.Chem., 2012;287:30653
  2. Uptake of L-glutamate into rat brain synaptic vesicles: effect of inhibitors that bind specifically to the glutamate transport.
    Roseth et al.
    J.Neurochem., 1995;65:96
  3. Inhibitors of amino acid uptake into vesicles.
    Fonnum et al.
    J.Neurochem., 1994;63:Suppl. 1 S49A

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Chicago Sky Blue 6B

The citations listed below are publications that use Tocris products. Selected citations for Chicago Sky Blue 6B include:

1 Citation: Showing 1 - 1


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Chicago Sky Blue 6B

There are currently no reviews for this product. Be the first to review Chicago Sky Blue 6B and earn rewards!

Have you used Chicago Sky Blue 6B?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.