10 results for "Glutamate (EAAT) Transporter Inhibitors" in Products
Glutamate (EAAT) Transporter Inhibitors
Glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia), EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).
Functions of glutamate transporters include regulation of excitatory neurotransmission...
Selective non-transportable inhibitor of EAATs
| Chemical Name: | DL-threo-β-Benzyloxyaspartic acid |
| Purity: | ≥98% |
Potent and selective EAAT1 and EAAT2 blocker
| Chemical Name: | (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid |
| Purity: | ≥98% |
EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
| Chemical Name: | (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid |
Potent competitive inhibitor of L-glutamate uptake
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% |
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
| Chemical Name: | 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt |
| Purity: | ≥90% |
Selective non-substrate EAAT1 inhibitor
| Chemical Name: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile |
| Purity: | ≥98% |
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
| Alternate Names: | L-threo-β-Hydroxyaspartic acid |
| Purity: | ≥98% |
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
| Alternate Names: | trans-4-Carboxy-L-proline |
| Chemical Name: | L-trans-Pyrrolidine-2,4-dicarboxylic acid |
| Purity: | ≥97% |
Potent, non-substrate EAAT2 inhibitor
| Chemical Name: | N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine |
| Purity: | ≥98% |
Potent competitive inhibitor of L-glutamate uptake. Sodium salt of 7-Chlorokynurenic acid (Cat. No. 0237)
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid sodium salt |
| Purity: | ≥98% |
