CHPG Sodium salt

Key Product Details

Product Description

CHPG Sodium salt is a sodium salt of the selective mGlu₅ agonist CHPG (Cat. No. 1049).

Product Specifications for CHPG Sodium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CHPG Sodium salt

The following data is based on the product molecular weight 223.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	8.94 mL	44.72 mL	89.45 mL
2.5 mM	1.79 mL	8.94 mL	17.89 mL
5 mM	0.89 mL	4.47 mL	8.94 mL
25 mM	0.18 mL	0.89 mL	1.79 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Salt Antagonism of the mGlu5 agonist 2-chloro-5-hydroxyphenylglycine by the novel selective mGlu5 antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) in the thalamus. Br.J.Pharmacol. 1999 PMID: 10455248
• Bao Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischaemia. Brain Res. 2001 PMID: 11743947
• Doherty (RS)-2-Chloro-5-hydroxyphenylglycine (CHPG) activates mGlu₅, but not mGlu₁, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 1997 PMID: 9144665

Product Documents for CHPG Sodium salt