Blocker of the slow delayed rectifier K+
= 1-10 μ
M). Also blocks the CFTR chloride current (ICFTR
= 19 μ
M). (-)-[3R,4S]-Chromanol 293B
(Cat. No. 1475) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKS), inhibits the CFTR Cl- current.
Bachmann et al.
Naunyn Schmiedebergs Arch.Pharmacol., 2001;363:590
Time-dependent block of the slowly activating delayed rectifier K+ current by chromanol 293B in guinea-pig ventricular cells.
Fujisawa et al.
Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes.
Sun et al.
The citations listed below are publications that use Tocris products. Selected citations for Chromanol 293B include:
Showing Results 1 - 2 of 2