ci-IP3/PM
Chemical Name: 6-O-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-2,3-O-(1-methylethylidene)-D-myo-Inositol 1,4,5-tris[bis[(1-oxopropoxy)methyl]phosphate]
Purity: ≥98%
Biological Activity
ci-IP3/PM is a caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores.F 127 (Cat. No. 6253) for the solubilization of ci-IP3/PM is also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Background References
-
Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate.
Dakin and Li et al.
Cell Calcium, 2007;42:291 -
Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3.
Lock et al.
Cell Calcium, 2017; -
Endothelin-1 and IP3 induced Ca2+ sparks in pulmonary arterial smooth muscle cells.
Zhang et al.
J.Cardiovasc.Pharmacol., 2004;44:S121
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