Ciclopirox

Key Product Details

Product Description

Ciclopirox is a pan-histone demethylase inhibitor. Exhibits no significant effect on histone deacetylases. Inhibits MYC-signaling and proliferation of neuroblastoma cells. Promotes Cdc25A-degradation in cancer cells. Antifungal.

Product Specifications for Ciclopirox

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ciclopirox

The following data is based on the product molecular weight 207.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.82 mL	24.12 mL	48.25 mL
5 mM	0.96 mL	4.82 mL	9.65 mL
10 mM	0.48 mL	2.41 mL	4.82 mL
50 mM	0.10 mL	0.48 mL	0.96 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• Yang Targeting histone demethylases in MYC-driven neuroblastomas with ciclopirox. Cancer Res. 2017 PMID:  28684529
• Shen Ciclopirox inhibits cancer cell proliferation by suppression of Cdc25A. Genes Cancer 2017 PMID: 28680535

Product Documents for Ciclopirox