Cilengitide

Catalog # Availability Size / Price Qty
5870/10
Cilengitide
1 Image
Description: Potent and selective inhibitor of integrins αvβ3 and αvβ5
Alternative Names: EMD121974

Purity: ≥95%

Product Details
Citations (3)
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Biological Activity

Cilengitide is a potent and selective inhibitor of integrins αvβ3 and αvβ5 (IC50 values are 4.1 and 70 nM, respectively). Exhibits ~10-fold selectivity over gpIIb/IIIa. Increases endothelial monolayer permeability. Also exhibits antiangiogenic activity.

Technical Data

M.Wt:
588.66
Formula:
C27H40N8O7
Sequence:
RGDFV

(Modifications: Phe-4 = D-Phe, Val-5 = Me-Val, Cyclized)

Solubility:
Soluble to 10 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
188968-51-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Cilengitide

The citations listed below are publications that use Tocris products. Selected citations for Cilengitide include:

3 Citations: Showing 1 - 3

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