Irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist; inhibits Ca2+
= 800 nM) and [32
P]NAADP binding (IC50
= 15 μ
M). Stereoisomer of trans-Ned 19
(Cat. No. 3954). Fluorescently labels NAADP receptors in intact cells (excitation 351 and 365 nm using an ultraviolet Argon laser).
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All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Identification of a chemical probe for NAADP by virtual screening.
Naylor et al.
The citations listed below are publications that use Tocris products. Selected citations for cis-Ned 19 include:
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