Claudin-11 Antibody (SR1352) - BSA Free

Name: Claudin-11 Antibody (SR1352) - BSA Free
Brand: Novus Biologicals
SKU: NBP3-21885
Price: 399 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-21885

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1352 expressed in HEK293

Format

BSA Free

View all Claudin-11 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Claudin-11 (Uniprot #: O75508)

Specificity

Detects endogenous levels of total Claudin-11

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Claudin-11 Antibody (SR1352) - BSA Free

Western Blot: Claudin-11 Antibody (SR1352) [NBP3-21885] -

Western Blot: Claudin-11 Antibody (SR1352) [NBP3-21885] - Western blot analysis using NBP3-21885 in SH-SY5Y cell lysate.

Applications for Claudin-11 Antibody (SR1352) - BSA Free

Application

Recommended Usage

Flow Cytometry

1:100

Western Blot

1:500-1:2000

Flow Cytometry Panel Builder

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Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

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Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Claudin-11

Oligodendrocyte specific protein belongs is a major component of central nervous system myelin that is necessary for normal CNS function. The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, and are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that the Claudin 11 protein determines the permeability between layers of myelin sheaths via focal adhesion and with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Alternate Names

Claudin11, CLDN11, OSP, OTM

Gene Symbol

CLDN11

Additional Claudin-11 Products

Product Documents for Claudin-11 Antibody (SR1352) - BSA Free

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Certificate of Analysis

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Product Specific Notices for Claudin-11 Antibody (SR1352) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.