CLCN1 Antibody (0P2M8)

Name: CLCN1 Antibody (0P2M8)
Brand: Novus Biologicals
SKU: NBP3-33303
Price: 449 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-33303

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 0P2M8

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Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 889-988 of human CLCN1 (NP_000074.3).

Sequence:
NTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESPGLEEELADILQGPSLRSTDEEDEDELIL

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

109 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CLCN1 Antibody (0P2M8)

Western Blot: CLCN1 Antibody (0P2M8) [NBP3-33303] -

Western Blot: CLCN1 Antibody (0P2M8) [NBP3-33303] - Western blot analysis of various lysates, using CLCN1 Rabbit mAb at 1:20000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 60s.

Applications for CLCN1 Antibody (0P2M8)

Application

Recommended Usage

ELISA

Recommended starting concentration is 1 ug/mL

Western Blot

1:2000 - 1:20000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CLCN1

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) whichdemonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encodedby this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause twoforms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia(Thomsen). (provided by RefSeq)

Long Name

Chloride channel protein 1

Alternate Names

ClC-1, CLC1

Gene Symbol

CLCN1

Additional CLCN1 Products

Product Documents for CLCN1 Antibody (0P2M8)

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Certificate of Analysis

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Product Specific Notices for CLCN1 Antibody (0P2M8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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