Biological ActivityCNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine (Cat. No. 3548); releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2 receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Desensitized D2 autoreceptors are resistant to trafficking.
Robinson et al.
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