Coagulation Factor II/Thrombin Antibody (GMA-020) - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-29813

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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # GMA-020

Format

Azide and BSA Free
View all Coagulation Factor II/Thrombin Primary Antibodies »

Product Specifications

Immunogen

purified human thrombin.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Relevant Entrez Gene Numbers: NM_000506

Scientific Data Images

Western Blot: Coagulation Factor II/Thrombin Antibody (GMA-020) [NBP2-29813]

Western Blot: Coagulation Factor II/Thrombin Antibody (GMA-020) [NBP2-29813]

Western Blot: Coagulation Factor II/Thrombin Antibody (GMA-020) [NBP2-29813] - 2ug of human thrombin was probed with anti-Thrombin, clone GMA-020 (1ug/ml). Arrow indicates thrombin (non reduced) (~31kDa).

Applications

Application
Recommended Usage

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS with 1.0% mannitol, pH 7.4

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Coagulation Factor II/Thrombin

Proteinase-activated receptor 3 (PAR3) is a member of the Proteinase-Activated Receptor subfamily. The enzyme thrombin is involved in the activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of PAR3 and other receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR3 expression has been documented in blood, bone marrow, lung, spleen, and vessel. ESTs have been isolated from head/neck, skeletal muscle, and skin libraries.

Alternate Names

F2, Thrombin

Gene Symbol

F2

UniProt

P00734

Additional Coagulation Factor II/Thrombin Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices

Relevant Entrez Gene Numbers: NM_000506

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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    • A: We currently have 1 neutralizing Thrombin antibody (NBP1-95029), however it is an anti-human antibody and has only been validated in human samples. If you would like to test this antibody in mouse samples, you may be interested in participating in our Innovators Reward Program.
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Associated Pathways

Blood Coagulation Signaling Pathways Blood Coagulation Signaling Pathway Thumbnail